What are limitations of invasive mechanical ventilation for the treatment of status asthmaticus?

Updated: Jun 17, 2020
  • Author: Constantine K Saadeh, MD; Chief Editor: John J Oppenheimer, MD  more...
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Invasive mechanical ventilation is associated with increased hospital resource use, with prolonged length of stay and even a higher risk of developing pneumonia. The research for noninvasive ventilation should help in minimizing the frequency of invasive mechanical ventilation. [63] In addition, a single case report showed that status asthmaticus in a 12-year-old boy with subcutaneous emphysema and pneumomediastinum resulted in worsening of both of the conditions with noninvasive ventilation. Further research is needed in this area. [64] When in doubt, mechanical invasive ventilation should be considered first in patients with significant respiratory distress who are not responding to the usual aggressive pharmacological and appropriate oxygenation. It is considered the safest approach in a patient who is in severe status asthmaticus, particularly with secondary respiratory failure. It is not, however, without adverse effects or complications. Pneumothorax and idiopathic hemothorax have both been reported. [65]

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