What is the role of positive end-expiratory pressure (PEEP) in the treatment of status asthmaticus?

Updated: Jun 17, 2020
  • Author: Constantine K Saadeh, MD; Chief Editor: John J Oppenheimer, MD  more...
  • Print

The use of positive end-expiratory pressure (PEEP) is controversial. A patient with status asthmaticus who is in respiratory failure and on mechanical ventilation usually has a significant amount of air trapping that results in intrinsic PEEP, which may be worsened by maintaining PEEP during exhalation. However, some patients may benefit from the addition of PEEP, perhaps owing to the maintenance of airway patency during exhalation. Thus, in a patient who remains refractory to the initial ventilatory settings with no or very low PEEP, cautiously increasing the PEEP may prove beneficial.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!