What is the efficacy of venoocclusive extracorporeal membrane oxygenation (ECMO) for the treatment of status asthmaticus?

Updated: Jun 17, 2020
  • Author: Constantine K Saadeh, MD; Chief Editor: John J Oppenheimer, MD  more...
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Answer

Steinack et al report that venoocclusive extracorporeal membrane oxygenation (ECMO) was effective in a 25-year-old pregnant woman. [59] The patient failed to respond to the usual therapeutic modalities for status asthmaticus, including the typical medications discussed as well as pressure control ventilation with high inspiratory pressures. ECMO as mentioned should always be considered with status asthmaticus and respiratory failure with inadequate response to pressure control ventilation, antimuscarinic drugs, intravenous beta-agonists, intravenous methylprednisolone, and magnesium sulfate. Continuous positive airway pressure therapy has been used for support of status asthmaticus. Noninvasive positive-pressure ventilation has been shown to "splint" the airways, allowing for better exhalation and emptying. [60]


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