What is the role of sedatives in the treatment of status asthmaticus?

Updated: Jun 17, 2020
  • Author: Constantine K Saadeh, MD; Chief Editor: John J Oppenheimer, MD  more...
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Answer

Patients may benefit from sedatives in very small doses and under controlled, monitored settings. Sedatives should be used judiciously, if at all. For example, lorazepam (0.5 or 1 mg intravenously) could be used for patients who are very anxious and are undergoing appropriate and aggressive bronchodilator therapy. More powerful agents (eg, oxybutynin) can be administered to intubated patients to achieve sedative, amnestic, and anxiolytic effects.

In the past several years, new therapies have been developed in patients with severe and resistant status asthmaticus despite mechanical ventilation.


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