How long does it take for corticosteroid therapy to become effective in the treatment of status asthmaticus?

Updated: Jun 17, 2020
  • Author: Constantine K Saadeh, MD; Chief Editor: John J Oppenheimer, MD  more...
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Answer

Corticosteroid action usually requires at least 4-6 hours to occur following corticosteroid administration because protein synthesis is required before the initiation of a corticosteroid’s anti-inflammatory effects. Because of this, patients with status asthmaticus must depend on other supportive measures (eg, beta2-agonists, oxygen, adequate ventilation) in their initial treatment while awaiting the action of corticosteroids. The usual dose is oral prednisone at 1-2 mg/kg daily.


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