What is the significance of bronchospasms and increased airway resistance during oscillation testing for status asthmaticus?

Updated: Jun 17, 2020
  • Author: Constantine K Saadeh, MD; Chief Editor: John J Oppenheimer, MD  more...
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Answer

Bronchospasms and increased large-airway resistance appear as increases in resistance at higher (25-35 cycles/s) components of oscillation frequency. Additionally, a pattern of increased resistance with increasing airflow is typical of a large-airway bronchospasm. In such patients, resistance at the beginning and end of inspiration and expiration is at its minimum, with increased levels during midinspiration and midexpiration. In such patients, a deep inspiration is often followed by reflex bronchoconstriction and increased resistance for 30 seconds or more, signaling increased airway reactivity.


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