What is the pancreatic enzyme products (PEPs) dosing in PERT for the treatment of exocrine pancreatic insufficiency (EPI)?

Updated: Aug 12, 2021
  • Author: Samer Al-Kaade, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

Dosing for pancreatic insufficiency is as follows:

  • Initial oral lipase dose, 500 units/kg/meal

  • Lipase dose range, 500-2500 units/kg/meal

  • Maximum lipase dosage, 10,000 units/kg/day or 4000 units per gram of fat daily


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