What is the role of broad-spectrum antibiotics in the treatment of amebiasis?

Updated: Jul 19, 2019
  • Author: Vinod K Dhawan, MD, FACP, FRCPC, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Broad-spectrum antibiotics may be added to treat bacterial superinfection in cases of fulminant amebic colitis and suspected perforation. Bacterial coinfection of amebic liver abscess has occasionally been observed (both before and as a complication of drainage), and adding antibiotics to the treatment regimen is reasonable in the absence of a prompt response to nitroimidazole therapy.

Loperamide should be avoided in the treatment of amebic colitis. [74]


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