When is treatment of asymptomatic amebiasis indicated?

Updated: Jul 19, 2019
  • Author: Vinod K Dhawan, MD, FACP, FRCPC, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

In endemic areas, asymptomatic infections are not treated. In nonendemic areas, however, asymptomatic infection should be treated [66] ; luminal agents that are minimally absorbed by the GI tract (eg, paromomycin, iodoquinol, and diloxanide furoate) are best suited for such therapy. [67, 68] This recommendation is based on 2 arguments: first, that invasive disease may develop, and second, that shedding of E histolytica cysts in the environment is a public health concern. [4]

Asymptomatic E dispar infections should not be treated, but because this organism is a marker of fecal-oral contamination, educational efforts should be initiated. [4]


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