What is the histopathological hallmark of amebic colitis?

Updated: Jul 19, 2019
  • Author: Vinod K Dhawan, MD, FACP, FRCPC, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Amebic invasion through the mucosa and into submucosal tissues is the hallmark of amebic colitis; lateral extension through the submucosal tissues gives rise to the classic flask-shaped ulcer of amebic colitis (see the images below).

Histopathology of amebiasis. Image courtesy of Cen Histopathology of amebiasis. Image courtesy of Centers for Disease Control and Prevention.
Histopathology of typical flask-shaped ulcer of in Histopathology of typical flask-shaped ulcer of intestinal amebiasis. Image courtesy of Centers for Disease Control and Prevention.

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