What is pleuropulmonary amebiasis?

Updated: Jul 19, 2019
  • Author: Vinod K Dhawan, MD, FACP, FRCPC, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Pleuropulmonary amebiasis is most commonly the result of contiguous spread from a liver abscess rupturing through the right hemidiaphragm. [48] However, a case of amebic lung abscess acquired through hematogenous spread has been reported. The typical age group is 20-40 years. The male-to-female ratio is 10:1.

Approximately 10% of patients with amebic liver abscess develop pleuropulmonary amebiasis, which presents with cough, pleuritic pain, and dyspnea. A hepatobronchial fistula is an unusual problem characterized by the expectoration of sputum resembling anchovy paste. The trophozoites of E histolytica may be found in the sputum sample. Primary amebic pneumonia as a result of hematogenous spread has been reported, though rarely. [49]

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