How does the prevalence of amebiasis vary by sex?

Updated: Jul 19, 2019
  • Author: Vinod K Dhawan, MD, FACP, FRCPC, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Amebic colitis affects both sexes equally. [4] However, invasive amebiasis is much more common in adult males than in females. In particular, amebic liver abscess is 7-12 times more common in men than in women, with a predominance among men aged 18-50 years. The reason for this disparity is unknown, though hormonal effects may be implicated, as the prevalence of amebic liver abscess is also increased among postmenopausal women. Alcohol may also be an important risk factor.

Among prepubertal children, amebic liver abscess is equally common in both sexes. [4] Acuna-Soto et al noted that asymptomatic E histolytica infection is distributed equally between sexes. [41] Therefore, the higher proportion of adult males with invasive amebiasis may be due to a male susceptibility to invasive disease.

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