What is the role of lab testing in the diagnosis of adenovirus-related gastroenteritis?

Updated: Apr 15, 2021
  • Author: Sandra G Gompf, MD, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Consider stool Wright stain; ova and parasites examination; culture for bacterial enteric pathogens; assays for norovirus, rotavirus, and Cyclospora; and Clostridium difficile toxin assay.

In immunocompromised hosts, early identification of patients at risk for adenovirus disease by monitoring for viremia by PCR is beneficial; thus, some centers have adopted routine weekly surveillance measures for pediatric recipients of allogeneic hematopoietic stem cell transplants. If viremia is detected, then patients should be carefully evaluated for evidence of disease. Although viremia is self-limited in some patients, a rising viral load has been associated with invasive disease. [30]

 


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