What are the reference range findings for anticardiolipin antibodies?

Updated: Jul 22, 2021
  • Author: Tarek Hammad, MD; Chief Editor: Eric B Staros, MD  more...
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Answer

Answer

Enzyme-linked immunoassay (ELISA) is currently the test of choice. The reference range findings are as follows: [2]

  • Less than 15 immunoglobulin G (IgG) phospholipids units (GPL): Absent or none detected

  • Less than 12 immunoglobulin M (IgM) phospholipids units (MPL): Absent or none detected

  • Less than 12 immunoglobulin A (IgA) phospholipids units (APL): Absent or none detected

If the test is obtained to diagnose antiphospholipid syndrome, only medium to high titers of IgG or IgM antibodies (defined as >40 GPL or MPL, or >99th percentile [3] ) are considered a positive test result.


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