Which antiretroviral combination products are used to treat HIV infection?

Updated: Jul 01, 2019
  • Author: Nicholas John Bennett, MBBCh, PhD, MA(Cantab), FAAP; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Numerous antiretroviral combination products are available on the market to assist patients with compliance and decrease the daily number of tablets and capsules required (see Table 2, below).

Table 2. Antiretroviral Combination Products (Open Table in a new window)

Drug Content per Tablet/Capsule*

Brand Name

Adult Dose (≥40 kg)

Darunavir 800 mg

Cobicistat 150 mg

Emtricitabine 200 mg

Tenofovir AF 10 mg

Symtuza# 1 tab PO qd with food

Bictegravir 50 mg

Emtricitabine 200 mg

Tenofovir AF 25 mg

Biktarvy# 1 tab PO qd

Efavirenz 400 mg

Lamivudine 300 mg

Tenofovir DF 300 mg

Symfi Lo# 1 tab PO qHS on an empty stomach

Efavirenz 600 mg

Lamivudine 300 mg

Tenofovir DF 300 mg

Symfi# 1 tab PO qHS on an empty stomach

Dolutegravir 50 mg

Rilpivirine 25 mg

Juluca#

1 tab PO qd with a meal

Note: This is a complete once-daily regimen in adults who are virologically suppressed (HIV-1 RNA < 50 copies/mL) on a stable ART regimen for ≥6 months with no history of treatment failure and no known substitutions associated with resistance

Dolutegravir 50 mg

Lamivudine 300 mg

Dovato#

1 tab PO qd with or without food

Note: This a complete once-daily regimen in treatment-naïve adults with no known substitutions associated with resistance to dolutegravir or lamivudine

Elvitegravir 150 mg

Cobicistat 150 mg

Emtricitabine 200 mg

Tenofovir AF 10 mg

Genvoya# 1 tab PO qd

Elvitegravir 150 mg

Cobicistat 150 mg

Emtricitabine 200 mg

Tenofovir DF 300 mg

Stribild#

1 tab PO qd

Abacavir 600 mg

Lamivudine 300 mg

Epzicom

1 tab PO qd

Abacavir 600 mg

Dolutegravir 50 mg

Lamivudine 300 mg

Triumeq

1 tab PO qd

Abacavir 300 mg

Lamivudine 150 mg

Zidovudine 300 mg

Trizivir

1 tab PO bid

Efavirenz 600 mg

Emtricitabine 200 mg

Tenofovir DF 300 mg

Atripla#

1 tab PO qd on empty stomach

Note: May be used alone as a complete regimen or in combination with other ARTs

Emtricitabine 200 mg

Rilpivirine 25 mg

Tenofovir DF 300 mg

Complera#

1 tab PO qd with a meal

Emtricitabine 200 mg

Rilpivirine 25 mg

Tenofovir AF 25 mg

Odefsey#

1 tab PO qd with a meal

Emtricitabine 200 mg

Tenofovir DF 300 mg

Truvada

1 tab PO qd

CrCl 30-49 mL/min: 1 tab PO q48h

CrCl < 30 mL/min: Do not administer

Emtricitabine 200 mg

Tenofovir AF 300 mg

Descovy

1 tab PO qd

CrCl < 30 mL/min: Do not administer

Lamivudine 150 mg

Zidovudine 300 mg

Combivir

1 tab PO bid

Lamivudine 300 mg

Tenofovir DF 300 mg

Cimduo 1 tab PO qd

Doravirine 100 mg

Lamivudine 300 mg

Tenofovir DF 300 mg

Delstrigo# 1 tab PO qd with or without food

*Not indicated for patients requiring dosage adjustments (eg, weight < 40 kg, renal impairment, hepatic impairment, dose-limiting adverse effects) unless otherwise stated.

#Complete once-daily regimen


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