What are the International Antiviral Society-USA (IAS-USA) antiretroviral treatment recommendations for adults with HIV infection?

Updated: Jul 01, 2019
  • Author: Nicholas John Bennett, MBBCh, PhD, MA(Cantab), FAAP; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

In July 2014, the International Antiviral Society-USA (IAS-USA) released antiretroviral treatment recommendations for adults, including the following: [119, 120]

  • Initiate ART in all HIV-infected adults who are willing/ready to start therapy. CD4 count is no longer considered a criterion of when to start therapy.
  • Consider NRTI-sparing approaches rather than boosted protease inhibitor monotherapy.
  • For refractory cases, during the failing treatment regimen and before switching therapy, use rapid confirmation, perform resistance testing, and reevaluate.

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