What are the European AIDS Clinical Society (EACS) recommendations for management of HIV infection?

Updated: Mar 05, 2020
  • Author: Shelley A Gilroy, MD, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Updated 2013 guidelines from the European AIDS Clinical Society (EACS) advise that antiretroviral drugs be considered and actively discussed even with asymptomatic patients with HIV whose CD4 count is still higher than 500/μL. [111, 112] In addition, they address diagnosis and management of comorbid conditions, including the following:

  • Hypertension

  • Type 2 diabetes

  • Bone disease - Osteopenia, osteoporosis, osteomalacia, and osteonecrosis (fracture reduction is a newly addressed topic in the guidelines)

  • Dyslipidemia

  • Vitamin D deficiency

  • Kidney disease - Antiretroviral drug–associated nephrotoxicity, proximal renal tubulopathy

  • Liver disease - Increased liver enzymes, cirrhosis, hepatorenal syndrome

  • Lipodystrophy

  • Hyperlactemia and lactic acidosis

  • Sexual dysfunction (a new topic in the guidelines)

  • Depression

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