What is the CDC diagnostic algorithm for HIV diagnosis?

Updated: Jul 27, 2020
  • Author: Shelley A Gilroy, MD, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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To address the problem of confirmatory supplemental tests giving false-negative results early in the course of HIV infection, the CDC conducted two prospective evaluations of a new HIV diagnostic algorithm. The new diagnostic algorithm replaces the Western blot (WB) with an HIV-1/HIV-2 antibody differentiation assay as the supplemental test and includes an RNA test to resolve reactive immunoassay (IA) with negative supplemental test results. [102]

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