What is the prognosis of untreated HIV infection?

Updated: Jul 01, 2019
  • Author: Nicholas John Bennett, MBBCh, PhD, MA(Cantab), FAAP; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

The prognosis in patients with untreated HIV infection is poor, with an overall mortality rate of more than 90%. The average time from infection to death is 8-10 years, although individual variability ranges from less than 1 year to long-term nonprogression. Many variables have been implicated in HIV's rate of progression, including CCR5-delta32 heterozygosity, mental health, [79] concomitant drug or alcohol abuse, superinfection with another HIV strain, nutrition, and age.


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