What are the classes for antiretroviral agents used in the treatment of HIV infection?

Updated: Dec 02, 2019
  • Author: Nicholas John Bennett, MBBCh, PhD, MA(Cantab), FAAP; Chief Editor: Michael Stuart Bronze, MD  more...
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Highly active antiretroviral therapy (HAART) is the principal method for preventing immune deterioration. Classes of antiretroviral agents include the following:

  • Nucleoside reverse transcriptase inhibitors (NRTIs)

  • Protease inhibitors (PIs)

  • Nonnucleoside reverse transcriptase inhibitors (NNRTIs)

  • Fusion inhibitors

  • CCR5 co-receptor antagonists (entry inhibitors)

  • HIV integrase strand transfer inhibitors

  • Entry inhibitors (CD4-directed post-attachment inhibitors)

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