What is the prognosis of postpolio syndrome (PPS)?

Updated: Apr 28, 2014
  • Author: Hidehiro Takei, MD; Chief Editor: Adekunle M Adesina, MD, PhD  more...
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Postpolio syndrome (PPS) is a slowly progressive disease that is rarely fatal. However, patients with PPS commonly develop new disabilities that cause significant morbidity, such as orthopedic complications (eg, progressive instability of joints, osteoporosis, fractures, osteoarthrosis, scoliosis, and spondylosis), respiratory insufficiency (eg, progressive nocturnal hypoventilation), and neurologic complications related to skeletal deformity and to the use of medical supporting devices (eg, peripheral neuropathy).

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