Which gross findings are characteristic of spinal muscular atrophy (SMA)?

Updated: Apr 28, 2014
  • Author: Hidehiro Takei, MD; Chief Editor: Adekunle M Adesina, MD, PhD  more...
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In type I spinal muscular atrophy (SMA), atrophy of the anterior spinal nerve roots is seen in the spinal cord, whereas the posterior nerve roots are normal. [32] However, spinal cords in this affected age group are so small that evaluation is often difficult. The brain is unremarkable. No detailed gross neuropathologic findings have been reported in type II or III SMA.

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