What is the prevalence of hereditary spastic paraparesis (HSP)?

Updated: Apr 28, 2014
  • Author: Hidehiro Takei, MD; Chief Editor: Adekunle M Adesina, MD, PhD  more...
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Answer

Answer

The prevalence of hereditary spastic paraparesis (HSP) varies from study to study as a result of the marked differences in the classifications used and their included diagnoses. In Ireland, the prevalence of pure autosomal dominant HSP is 1.17/100,000 population, [9] whereas in southeast Norway, the HSP prevalence was estimated to be 7.4/100,000 population (pure autosomal dominant HSP, 4.5/100,000; complex autosomal dominant HSP, 1.0/100,000; and autosomal recessive HSP, 1.3/100,000). [10]


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