What is postpolio syndrome (PPS)?

Updated: Apr 28, 2014
  • Author: Hidehiro Takei, MD; Chief Editor: Adekunle M Adesina, MD, PhD  more...
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PPS is a clinical diagnosis and essentially one of exclusion. This condition is characterized by late-onset muscle weakness and fatigue in skeletal or bulbar muscles, unrelated to any known cause, in individuals with a previous history of an acute attack of paralytic poliomyelitis. [6] Survivors of the polio epidemics that occurred worldwide in the mid-20th century constitute a population at risk for PPS.

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