What is the role of sumatriptan (Imitrex) in the treatment of pediatric headache?

Updated: Jan 02, 2019
  • Author: J Ivan Lopez, MD, FAAN, FAHS; Chief Editor: George I Jallo, MD  more...
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Answer

Sumatriptan (Imitrex), a serotonin 5-HT1 receptor agonist that causes vasoconstriction, among other actions, is effective in aborting migraine (about 70% efficacy in adults). It is available as an oral tablet, nasal inhalant, transdermal, or subcutaneous patient autoinjection system (vials for injection). The injected form of sumatriptan works faster than the nasal spray or the oral form. New, needleless parenteral forms of sumatriptan are also available.


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