What causes pediatric migrainelike headache?

Updated: Jan 02, 2019
  • Author: J Ivan Lopez, MD, FAAN, FAHS; Chief Editor: George I Jallo, MD  more...
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It should be clarified that although true migraine is a primary headache disorder, sometimes a migrainelike headache can be secondary to a metabolic or vascular disease. This is the case, for instance, with MELAS (mitochondrial encephalomyopathy, lactic acidosis, stroke), a mitochondrial cytopathy, and with CADASIL (cerebral autosomal dominant angiopathy with subcortical infarcts and leukoencephalopathy), a genetically determined disease of small vessels in the brain. The headache attacks in these disorders are indistinguishable from those of primary, true migraine, but other symptoms and disease features are also present.

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