What are indications for prophylactic anticoagulation in hereditary and acquired hypercoagulability?

Updated: Jan 05, 2018
  • Author: Paul Schick, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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If a patient is known to have a lupus anticoagulant or a thrombophilia, it is important to avoid oral contraceptives and hormone replacement therapy. Also, prophylactic anticoagulation should be considered in patients with additional risk for venous thrombosis, such as immobilization or surgery.

The risk of venous thrombosis is considerably greater in patients with two hereditary thrombophilias or with a thrombophilia and an acquired hypercoagulable disorder. Prophylactic anticoagulation should be considered in these circumstances.

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