What are the indications for primary prophylaxis in hereditary and acquired hypercoagulability?

Updated: Jan 05, 2018
  • Author: Paul Schick, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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The goal of this article is not to review the management of thrombotic episodes, which is described in Deep Venous Thrombosis and Pulmonary Embolism. Management of specific prothrombotic disorders is detailed in the following Medscape reviews:

However, indications for anticoagulation to prevent thromboembolism in patients at risk should be considered (ie, primary anticoagulation or prophylaxis). Indications for primary prophylaxis include the following:

  • Prolonged hospitalization
  • Postoperative status
  • Immobilization
  • Certain orthopedic disorders
  • Active cancer

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