What are the benefits of testing for thrombophilia and antiphospholipid syndrome (lupus anticoagulants) in hereditary and acquired hypercoagulability?

Updated: Jan 05, 2018
  • Author: Paul Schick, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Answer

Some benefits may exist with testing patients for thrombophilia and antiphospholipid syndrome (lupus anticoagulants).The presence of more than one risk factor results in an incidence rate of venous thrombosis that is greater than the sum of the individual risks. For example, women with a prothrombotic mutation who are taking estrogen have a 25-fold greater risk of venous thrombosis than women without the mutation who are on estrogen. [23]


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