What are the challenges in the decision to order a workup for hereditary and acquired hypercoagulability?

Updated: Jan 05, 2018
  • Author: Paul Schick, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Answer

The decision to order a thrombophilia workup can be difficult, because the identification of an underlying thrombophilia might not affect therapeutic strategy. If thrombophilia is detected in a patient with no history of thromboembolism, anticoagulation is usually not necessary. Conversely, patients with recurrent thromboembolic events should be anticoagulated even if their workup uncovers no evidence of an underlying thrombophilia or a lupus anticoagulant.


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