What is Henoch-Schönlein purpura (HSP)?

Updated: Oct 06, 2020
  • Author: Irene S Pakos, DO; Chief Editor: Perumal Thiagarajan, MD  more...
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Henoch-Schönlein purpura (HSP) is a form of nonthrombocytopenic purpura due to hypersensitivity vasculitis and is primarily observed in children. [30, 31] The condition is usually benign, and it manifests in a variety of clinical symptoms, including urticaria and erythema, arthropathy and arthritis, gastrointestinal problems, and kidney involvement. Two cases of acute appendicitis have been reported. [24] On rare occasions, patients have life-threatening hemorrhage that requires blood and blood-product support. [33] Soluble urine transferrin receptor has been proposed a potential marker for HSP nephritis. [34]

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