Which lab tests are indicated in the monitoring of intravenous immunoglobulin (IVIG) therapy?

Updated: Jul 05, 2018
  • Author: Jessica Katz, MD, PhD, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

Laboratory tests may include the following:

  • Liver function tests

  • Renal function tests

  • CBC count with differential

  • Hepatitis screen to assess for possible disease transmission by IVIG

  • Immunoglobulin levels to exclude IgA deficiency: If no IgA antibodies are found, then anti-IgA antibody titers should be obtained.

  • Rheumatoid and cryoglobulin levels, because IVIG can cause hematological complications

Finally, store a small amount of serum used before each infusion for analysis in the event of infectious disease transmission.


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