Which diseases do not respond to intravenous immunoglobulin (IVIG)?

Updated: Jul 05, 2018
  • Author: Jessica Katz, MD, PhD, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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However, it does not work for all diseases; for example, a Korean study of 63 patients (ie, folliculitis decalvans hidradenitis suppurativa, folliculitis, furunculosis) with recalcitrant suppurative skin diseases reported that it helped 59% of patients, but with only a 20% success rate in treating hidradenitis. [11]

Diseases that are purely of hematological or clotting factor defects such as Degos disease or paroxysmal nocturnal hemoglobinuria do not respond to IVIG. [12]

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