What is the efficacy of intravenous immunoglobulin (IVIG) in the prevention of respiratory infections?

Updated: Jul 05, 2018
  • Author: Jessica Katz, MD, PhD, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

The broad range of applications of IVIG shows the importance of immunoglobulins in the immune homeostasis in healthy people.

Noteworthy to remember is that while IVIG replacement prevents severe and lower respiratory tract infections, it does not prevent upper respiratory tract and non-respiratory infections in persons with common variable immune deficiency. [8] The largest challenge faced in 2018 is identifying those persons with specific diseases who will respond to IVIG and what biomarkers might inform apposite therapy. [9, 10]


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