Which medications in the drug class Coagulation Factors are used in the treatment of Factor X Deficiency?

Updated: Mar 23, 2018
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Perumal Thiagarajan, MD  more...
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Answer

Coagulation Factors

Provides replacement for temporary correction of various coagulation factor deficiencies.

Factor X, human (Coagadex)

Factor X replacement that increases plasma levels of factor X and can temporarily correct the coagulation defect in these patients, as reflected by decrease in the aPTT and PT. Indicated for hereditary factor X deficiency for on-demand treatment and control of bleeding episodes. It is also indicated for perioperative management of bleeding in patients with mild hereditary factor X deficiency.

Factor IX complex (Bebulin, Bebulin VH, Profilnine SD)

Product made from pooled human plasma. Contains factors II, VII, IX, and X; protein C; and trace amounts of heparin to guard against thrombosis. The dose can be calculated depending on the concentration of protein C in a preparation. Preparations may vary.


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