What are proposed clinical applications for serum procalcitonin (PCT) measurement?

Updated: Jul 30, 2019
  • Author: Jiun-Lih Jerry Lin, MBBS, MS(Orth); Chief Editor: Eric B Staros, MD  more...
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Answer

Answer

Proposed applications of serum procalcitonin measurement include the following:

  • To aid the choice and timing of the initiation of antibiotic treatment (Procalcitonin Algorithm) for improved antibiotic stewardship
  • To assist with elucidating prognosis of severe localized infections (eg, pneumonia) [21]
  • To aid with elucidating prognosis of critically ill patients with systemic infection
  • Predicting the need of antibiotic treatment in sepsis and to shorten the duration of antibiotics required [22]
  • Use as independent predictor of graft failure late after renal transplantation [23]

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