When is serum procalcitonin (PCT) measurement indicated?

Updated: Jul 30, 2019
  • Author: Jiun-Lih Jerry Lin, MBBS, MS(Orth); Chief Editor: Eric B Staros, MD  more...
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Indications for serum procalcitonin measurement include the following:

  • To aid in the diagnosis and risk stratification of bacterial sepsis [11, 12]

  • To aid in the diagnosis of renal involvement in children with urinary tract infection

  • To aid in distinguishing bacterial from viral infections, including meningitis [13]

  • To monitor therapeutic response to antibacterial therapy and reduce antibiotic exposure [14, 15, 16, 17, 18]

  • To aid in the diagnosis of systemic secondary infection after surgery and in severe trauma, burns, and multiorgan failure [19]

  • To aid diagnosis of infected necrosis and associated systemic complications in acute pancreatitis [20]

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