What is the role of imaging studies in the workup of factor V deficiency?

Updated: Mar 09, 2021
  • Author: Olga Kozyreva, MD; Chief Editor: Perumal Thiagarajan, MD  more...
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Early and aggressive imaging studies are indicated, even with low suspicion for hemorrhage, after coagulation therapy is initiated, and may include the following:

  • Head computed tomography (CT) scan (noncontrast) - To assess spontaneous or traumatic hemorrhage

  • Body CT scan - Perform as indicated by clinical suspicion and anatomical location, to assess spontaneous or traumatic hemorrhage. May be performed with or without intravenous contrast, oral contrast, or both.

  • Head and spinal column MRI - To further assess spontaneous or traumatic hemorrhage

  • Radiograph for joint assessment - This is of limited value in an acute setting of hemarthrosis. Chronic degenerative joint disease is often present.

  • Special studies - Perform angiography and nucleotide bleeding scan as clinically indicated.

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