Which medications in the drug class Opioid Analgesics are used in the treatment of Bronchial Thermoplasty?

Updated: Mar 30, 2021
  • Author: Said A Chaaban, MD; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Opioid Analgesics

Induction of anesthesia is accomplished by using high doses of opioid. Pain control is essential to quality patient care. Analgesics ensure patient comfort, promote pulmonary toilet, and have sedating properties that are beneficial for patients who experience pain.

Fentanyl citrate (Duragesic, Abstral, Actiq, Fentora, Onsolis)

Fentanyl citrate is a synthetic opioid that is 75-200 times more potent than morphine sulfate and that has a much shorter half-life. It has less hypotensive effects and is safer in patients with hyperactive airway disease than morphine because of minimal-to-no associated histamine release.

The parenteral form is the DOC for conscious sedation analgesia. It is ideal for analgesic action of short duration during anesthesia and in the immediate postoperative period.

Fentanyl citrate is an excellent choice for short-duration (30-60 minutes) pain management and sedation and easy to titrate. It is easily and quickly reversed by naloxone.

After the initial parenteral dose, subsequent parenteral doses should not be titrated more frequently than q3h or q6h thereafter.

Morphine sulfate (Duramorph, Astramorph, MS Contin, Avinza, Kadian)

Morphine sulfate is the DOC for analgesia owing to its reliable and predictable effects, safety profile, and ease of reversibility with naloxone.

Various IV doses are used; it is commonly titrated until the desired effect is obtained.

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