What are considerations when interpreting C-terminal telopeptide test results?

Updated: Feb 18, 2020
  • Author: Carlos Solano Loran, MD; Chief Editor: Eric B Staros, MD  more...
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Answer

Answer

Reduced urinary excretion of beta-CTX and a consequent rise in the apparent serum beta-CTX concentration may result from reduced renal function.

In patients undergoing treatment with high doses of biotin (ie, >5 mg/day), a specimen should not be drawn until at least 8 hours after the biotin was last administered, to avoid assay interference from the biotin.

Erroneous results may be derived from any test containing monoclonal mouse antibodies in a patient who has been treated with monoclonal mouse antibodies or has received them for diagnostic purposes.


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