What is the role of colonoscopy and endoscopy in the workup of factor XIII (FXIII) deficiency?

Updated: Aug 01, 2019
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Perumal Thiagarajan, MD  more...
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When indicated, perform other procedures, such as colonoscopy, in persons without hemophilia. Evaluate persistent GI tract bleeding without an apparent cause using endoscopy and colonoscopy to exclude underlying lesions. Persistent genitourinary tract bleeding requires evaluation for nephrolithiasis, tumors, or obstruction. If a biopsy is needed, patients require replacement therapy prior to and following the procedure until the biopsy site has healed.

Invasive lifesaving procedures should be performed in patients with inhibitors only in concert with appropriate treatment.

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