What is the role of liver function tests in the workup of factor XIII (FXIII) deficiency?

Updated: Apr 02, 2018
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Perumal Thiagarajan, MD  more...
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Answer

Perform liver function tests; kidney function tests; HIV-1 and HIV-2 antigen and antibody tests; hepatitis A (HAV), hepatitis B (HBV), hepatitis C (HCV), hepatitis D, and hepatitis E antigen/antibody levels; and other tests as needed.

Assess a-fetoprotein levels and other tumor markers as needed in patients with chronic hepatitis.

FXIII, which is involved in wound healing and angiogenesis, may be detectable by highly sensitive chemiluminescent ELISAs in tiny volumes of tear. This concept may provide a tool for monitoring FXIII subunit and complex levels in pathological conditions. [100]


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