How is a diagnosis of acquired factor XIII (FXIII) deficiency confirmed?

Updated: Aug 01, 2019
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Perumal Thiagarajan, MD  more...
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Acquired systemic disorders, including decompensated DIC and liver disease, require standard tests to confirm the diagnosis.

Caution is warranted in obtaining blood samples for any coagulation assays from heparinized central lines because of the effect of large amounts of heparin on any coagulation test that depends on thrombin generation.

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