Which lab tests are performed in the workup of factor XIII (FXIII) deficiency?

Updated: Apr 02, 2018
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Perumal Thiagarajan, MD  more...
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Answer

The following routine tests are the first step in the evaluation of any bleeding disorder:

  • aPTT

  • PT

  • Thrombin

  • Clottable fibrinogen level

  • Platelet count

  • Bleeding time (after ascertaining that the patient was not on antiplatelet drugs for at least the preceding 5 d)

However, these tests cannot be used to screen for FXIII deficiency because the results would be within reference ranges in a patient with isolated severe FXIII deficiency. [4]


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