Which medications in the drug class Immunomodulators are used in the treatment of Pediatric Multiple Sclerosis?

Updated: Jan 30, 2019
  • Author: Alice K Rutatangwa, DO, MSc; Chief Editor: Amy Kao, MD  more...
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Answer

Immunomodulators

Immunomodulators or receptor modulators are indicated for the treatment of adults with relapsing forms of MS. They help to slow the accumulation of physical disability and decrease the frequency of clinical exacerbations.

Interferon beta-1b (Betaseron, Extavia)

Immunomodulators or receptor modulators are indicated for the treatment of adults with relapsing forms of MS. Shown to slow the accumulation of physical disability and decrease the frequency of clinical exacerbations.

Interferon beta 1a (Avonex, Rebif)

The exact mechanism by which interferon beta-1a exerts its effects is not fully defined. Interferon beta inhibits the expression of proinflammatory cytokines, including interferon gamma, which is believed to be a major factor responsible for triggering the autoimmune reaction leading to MS.


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