Which conditions are associated with beta-cell destruction caused by decreased insulin levels?

Updated: Jan 02, 2019
  • Author: Saranya Buppajarntham, MD; Chief Editor: Eric B Staros, MD  more...
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Answer

Answer

Conditions associated with beta-cell destruction include the following:

  • Post pancreatectomy

  • Chronic pancreatitis

  • Autoimmune destruction

  • Type 1 diabetes

In type 2 diabetes (late stage), beta cells fail to secrete insulin for maintaining the blood glucose level, owing to insulin resistance and genetic defect. [6]

Increased insulinlike growth factor levels are associated with non–beta cell tumors.


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