What is glucagon?

Updated: Jul 24, 2019
  • Author: Cory Wilczynski, MD; Chief Editor: Eric B Staros, MD  more...
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Glucagon consists of 29 amino acids in a single-chain polypeptide with a molecular weight of 3485. It is produced by the alpha cells of the exocrine part of the pancreas and is removed by the liver and kidneys. Because glucagon has a half-life of just 3-6 minutes, collection of serum glucagon needs to occur in a chilled collecting tube with the immediate addition of a proteolytic enzyme inhibitor.

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