What is the clinical interpretation of fructosamine?

Updated: Oct 01, 2019
  • Author: Justyna Kotus, MD; Chief Editor: Eric B Staros, MD  more...
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Fructosamine levels indicate the average level of blood glucose control over the past 2-3 weeks. [2, 3, 4] In individuals with diabetes mellitus, an increased level of serum fructosamine is associated with prolonged hyperglycemia for 2-3 weeks prior to testing. The higher the fructosamine value, the poorer the degree of glycemia control. A trend from high to normal fructosamine levels may indicate that changes to a person's treatment regimen are effective.

Since the fructosamine concentrations of people with well-controlled diabetes may overlap with those of people who are not diabetic, the fructosamine test is not useful as a screening test for diabetes.

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