How are glucose samples collected for testing?

Updated: Jul 22, 2021
  • Author: Setu K Patolia, MD, MPH; Chief Editor: Sridevi Devaraj, PhD, DABCC, FAACC, FRSC, CCRP  more...
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Serum, plasma, urine, and CSF are acceptable for collection and can be handled as follows [5] :

  • Serum - Use standard venipuncture techniques to collect serum in glass or plastic tubes with or without gel barriers; make sure that complete clot formation has occurred pre-centrifugation
  • Plasma - Lithium heparin, sodium heparin, sodium fluoride/potassium oxalate, and ethylenediamine tetraacetic acid (EDTA) are acceptable for anticoagulation
  • Urine - 5 mL glacial acetic acid should be added to the container prior to starting collection in order to preserve a 24-hour sample 
  • CSF - Immediate processing is needed to avoid falsely low results 

At 2-8ºC, plasma/serum specimens can be stored for 7 days, urine for 2 hours, and CSF for more than 1 month.

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