How are specimens collected for serum CA 125 testing?

Updated: Jan 10, 2020
  • Author: Gentry George T King, MD; Chief Editor: Eric B Staros, MD  more...
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Specimen: Blood or serum

Collection method: Routine venipuncture

Patient preparation: No patient preparation is needed prior to the collection of the sample

Container: Blood is collected into a purple-top tube with ethylenediaminetetraacetic acid (EDTA)

Interactions: Heparin and oxalate may interfere with testing; these should be avoided

Storage: The American Association for Clinical Chemistry (AACC) recommends analyzing serum shortly after centrifugation of the obtained blood specimen. The serum specimen can then be stored at either 4°C (1-5 days) or -20°C (2 weeks to 3 months) in the short term or -70°C in the long term to ensure stability. [21]

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